Grants

NIH NINDS U24 NS129893 (Impact score 20) PI: Fuyixue Wang
Advancing fMRI acquisition through dissemination of EPTI – an efficient distortion-free multi-contrast imaging technology
The goal of this project is to advance fMRI studies through the dissemination of EPTI, an efficient distortion-free multi-contrast imaging technology.

NIH NIBIB R01 EB036507 (Impact score 20, percentile 4%) PI: Fuyixue Wang
Developing next-generation imaging technologies for in-vivo mesoscale diffusion MRI and microstructure imaging
The goal of this project is to develop novel acquisition and reconstruction methods for in-vivo diffusion MRI at mesoscopic resolutions and/or high b-values.

NIH-NIA K99/R00 AG083056 (Impact score 18) PI: Zijing Dong
Imaging brain-wide subarachnoid and perivascular cerebrospinal fluid flow in aging and Alzheimer’s disease

The goal of this project is to obtain previously unavailable knowledge on brain-wide CSF flow dynamics and pathways in the human brain using novel MR imaging technologies, and investigate the alteration of CSF flow in aging and Alzheimer’s disease.

NIH NIBIB P41 EB030006 TRD2 (renewal pending) Co-lead: Fuyixue Wang; Co-investigator: Zijing Dong
Center for Mesoscale Mapping – Acquisition Technology for Functional and Quantitative MRI at the Mesoscopic Scale

The goal of the Center for Mesoscale Mapping is to drive the convergence of microscopic- and macroscopic- scale evaluation of brain structure and function for human translational neuroscience.

NIH R01 EB033206 Site-PI: Fuyixue Wang
An acquisition and reconstruction framework to enable mesoscale human fMRI on clinical 3 Tesla scanners
The goal of the project is to improve the sensitivity and specificity of non-BOLD fMRI.

NIH NINDS U24NS137077 Co-investigator: Fuyixue Wang
Connectome 2.0: A BRAIN Technology Integration and Dissemination Resource for Ultra-High Gradient Magnetic Resonance Imaging of Human Brain Circuits Across Scales
Implement and disseminate advanced image reconstruction, processing, and quality assurance pipelines tailored for ultra-high gradient strength diffusion MRI.

NIH NINDS U19NS128613 Co-investigator: Zijing Dong, Fuyixue Wang
Neural circuit control of fluid and solute clearance during sleep
This proposal aims to identify the neural circuit mechanisms that control periarterial cerebrospinal fluid (CSF) pumping and glymphatic clearance of fluid and solutes.

NIH R01 AT011429 Co-investigator: Zijing Dong
Neuroimaging the impact of respiration and respiratory-gated neuromodulation on human glymphatic physiology
This project will test the role of both respiratory and noninvasive neurostimulation interventions in regulating CSF flow.

NIH-NCI R01 CA211080-06A1 Co-investigator: Fuyixue Wang
Development of multinuclear MRI for image guided therapy of glioma patients
This project aims to develop and translate high-resolution MRSI methods to guide surgical removal and metabolic interventions of gliomas.

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